School of Clinical Medicine (ETDs)

Permanent URI for this communityhttps://hdl.handle.net/10539/37930

Browse

Filters

2022 - 20242

Settings

Subject: search.filters.subject.Emergency Department

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Adequacy of Availability of Antidotes for Common and Critical Drug Poisonings and Doctors’ Perspectives Thereof: A Study in Teaching Hospitals in the Southern Gauteng City-Region
    (University of the Witwatersrand, Johannesburg, 2022-04) Fitchett, Margaret Penelope; Saffy, Patricia M.; Lewis, Carolyn M.
    Background: Drug poisoning is an important area of study in South Africa (SA) as a treatable cause of mortality. While research has been conducted on poisoning, there is a paucity of literature on the availability of antidotes in SA. Objectives: To assess the availability of antidotes in selected teaching hospitals in the Southern Gauteng City-Region and to explore doctors’ experiences of antidote supply. Methods: A data sheet assessing the availability of antidotes in the Emergency Departments (EDs) and pharmacies was completed in person at each of the teaching hospitals. A questionnaire exploring experiences of antidote supply was distributed to 126 doctors working in the EDs. Results: N-acetylcysteine, atropine, diazepam, clonazepam, sodium bicarbonate, vitamin K, calcium gluconate, naloxone, ethanol and pyridoxine were present in all EDs. Doctors reported organophosphate poisoning and paracetamol overdose as the most common drug poisonings (81.7% and 14.3% of 126 respondents respectively). Most doctors experienced no supply issues for N-acetylcysteine, calcium gluconate, sodium bicarbonate or pyridoxine (85.7%, 83.3%, 87.3% and 75.4% of 126 respondents respectively). Conclusion: The antidotes to the most common poisonings reported by doctors were present in all EDs. However, concerns were raised about consistency of supply which will be an important avenue for further research.
  • Thumbnail Image
    Item
    Knowledge, attitudes and practices of clinician management of adults presenting with acetylcholinesterase inhibitor poisoning
    (University of the Witwatersrand, Johannesburg, 2024) Redant, Dean Patrick
    Background: Acetylcholinesterase inhibitor (AChE-I) poisoning is a common cause of deliberate self-harm in South Africa (SA). Whilst there is existing literature on the epidemiology and management of AChE-I poisoning, there is a lack of research on the South African clinician’s knowledge, attitudes and clinical practice when managing these patients. Objectives: To describe the knowledge, attitudes and practices (KAP) of clinicians when managing adult patients with AChE-I poisoning in academic emergency departments (ED) in Southern Johannesburg, Gauteng. To describe the correlation between the clinician’s demographics and experience to their knowledge, attitudes and practices in this setting. Methods: One hundred and forty-five clinicians completed a structured questionnaire used to gather data on clinicians’ knowledge, attitudes and practices (KAP) with regards to their management of patients with AChE-I poisoning. Descriptive and inferential statistics were used to analyse the data and to infer correlation between clinician’s KAP vs clinician’s demographics and experience. Results: One hundred and forty-five questionnaires from 5 EDs were completed and analysed. Of which 86 (59%) of participants were female and 59 (41%) were male. The majority of participants were under the age of 40 (84%) and employed as Grade 1 Medical Officers (39%). Years of experience were divided into <2 years, 2 – 5 years and ≥5 years with each group representing a third of the sampled population. Clinician average knowledge scores on AChE-I poisoning were good (77.9% n= 12.46/16) with scores improving predictably with years of experience (72.5% in <2 years to 83% in ≥5 years). Attitudes towards managing patients with AChE-I poisoning were overall neutral. Clinician practices varied greatly, particularly with adjustment of atropine infusions and adjunctive treatments used. Conclusion: Clinicians had an overall good knowledge of AChE-I poisoning which improved predictably with greater experience managing these patients. Practices were highly varied across all demographic groups despite access to protocols in most departments studied. Attitudes were generally neutral with no clear impacting factors. Clinicians agreed unequivocally that the public health system did not provide sufficient primary preventative care in order to address the underlying factors driving patients to self-harm. This research revealed that the medical and psychosocial management of adult patients with AChE-I poisoning can be improved upon through specific clinician training.