A role for transforming growth factor alpha and its receptor in human oesophageal cancer

Simple item page
dc.contributor.authorJones, Gregory Justin
dc.date.accessioned2018-10-22T08:47:42Z
dc.date.available2018-10-22T08:47:42Z
dc.date.issued1993
dc.descriptionA dissertation submitted to the Faculty of Science, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Master of Science.en_ZA
dc.description.abstractA member of the epidermal growth factor (EGF) family; transforming growth factor alpha (TGF-a) shares significant homology with EGF and binds to the EGF receptor (EGF-R). Like EGF TGF-a plays important roles in normal physiological processes; but, as its name signifies, it has potent transforming ability; often associated with autocrine stimulatory mechanisms. The purpose of this study is to investigate a possible role for TGF-a and its receptor in certam human oesophageal squamous cell carcinoma (SCC) cell lines - namely, WHCO-I, -3 and -5. The wellstudied A431 epidermoid. carcinoma cell line was used throughout for control purposes. (Abbreviation abstract)en_ZA
dc.description.librarianAndrew Chakane 2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/25852
dc.language.isoenen_ZA
dc.subjectTransforming growth factors.en_ZA
dc.subjectEpidermal growth factor.en_ZA
dc.subjectEsophagus -- Cancer.en_ZA
dc.titleA role for transforming growth factor alpha and its receptor in human oesophageal canceren_ZA
dc.typeThesisen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Jones Gregory Justin._A role for transforming grow.pdf
Size:
3.49 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
ETD Collection