Changing Knowledge and Attitudes Towards HIV Treatment‑as‑Prevention and “Undetectable=Untransmittable”: A Systematic Review

Simple item page
dc.contributor.authorJacob Bor
dc.contributor.authorCharlie Fischer
dc.contributor.authorMirva Modi
dc.contributor.authorBruce Richman
dc.contributor.authorCameron Kinker
dc.contributor.authorRachel King
dc.contributor.authorSarah K. Calabrese
dc.contributor.authorIdah Mokhele
dc.contributor.authorTembeka Sineke
dc.contributor.authorThembelihle Zuma
dc.contributor.authorSydney Rosen
dc.contributor.authorTill Bärnighausen
dc.contributor.authorKenneth H. Mayer
dc.contributor.authorDorina Onoya2
dc.date.accessioned2024-09-27T13:18:06Z
dc.date.available2024-09-27T13:18:06Z
dc.date.issued2021-04-30
dc.description.abstractPeople on HIV treatment with undetectable virus cannot transmit HIV sexually (Undetectable=Untransmittable, U=U). However, the science of treatment-as-prevention (TasP) may not be widely understood by people with and without HIV who could beneft from this information. We systematically reviewed the global literature on knowledge and attitudes related to TasP and interventions providing TasP or U=U information. We included studies of providers, patients, and communities from all regions of the world, published 2008–2020. We screened 885 papers and abstracts and identifed 72 for inclusion. Studies in high-income settings reported high awareness of TasP but gaps in knowledge about the likelihood of transmission with undetectable HIV. Greater knowledge was associated with more positive attitudes towards TasP. Extant literature shows low awareness of TasP in Africa where 2 in 3 people with HIV live. The emerging evidence on interventions delivering information on TasP suggests benefcial impacts on knowledge, stigma, HIV testing, and viral suppression. Review was pre-registered at PROSPERO: CRD42020153725
dc.description.submitterPM2024
dc.facultyFaculty of Health Sciences
dc.identifier.urihttps://hdl.handle.net/10539/41171
dc.language.isoen
dc.schoolSchool of Public Health
dc.subjectSystematic review · Treatment-as-Prevention · Undetectable=Untransmittable
dc.subject.otherSDG-3: Good health and well-being
dc.titleChanging Knowledge and Attitudes Towards HIV Treatment‑as‑Prevention and “Undetectable=Untransmittable”: A Systematic Review
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
10461_2021_Article_3296.pdf
Size:
1.23 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.43 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
SA-MRC/Wits Agincourt Unit (Research Outputs/Publications)