Transactional sex and incident HIV infection in a cohort of young women from rural South Africa

dc.contributor.authorKelly Kilburn
dc.contributor.authorMeghna Ranganathan
dc.contributor.authorMarie C.D. Stoner
dc.contributor.authorJames P. Hughes
dc.contributor.authorCatherine MacPhail
dc.contributor.authorYaw Agyei
dc.contributor.authorF. Xavier Gomez-Oliv
dc.contributor.authorKathleen Kahn
dc.contributor.authorAudrey Pettifor
dc.date.accessioned2023-09-12T11:58:54Z
dc.date.available2023-09-12T11:58:54Z
dc.date.issued2018
dc.description.abstractObjective: In sub-Saharan Africa, young women who engage in transactional sex (the exchange of sex for money or gifts) with a male partner show an elevated risk of prevalent HIV infection. We analyse longitudinal data to estimate the association between transactional sex and HIV incidence. Design: We used longitudinal data from a cohort of 2362 HIV-negative young women (aged 13–20 years) enrolled in a randomized controlled trial in rural, South Africa who were followed for up to four visits over 6 years. Methods: The effect of transactional sex on incident HIV was analysed using stratified Cox proportional hazards models and cumulative incidence curves. Risk ratios were estimated using log-binomial models to compare the effects across visits. Results: HIV incidence was higher for young women that reported transactional sex (hazard ratio 1.59, 95% confidence interval 1.02–2.19), particularly when money and/ or gifts were received frequently (at least weekly) (hazard ratio 2.71, 95% confidence interval 1.44–5.12). We also find that effects were much stronger during the main trial and dissipate at the postintervention visit, despite an increase in both transactional sex and HIV. Conclusion: Transactional sex elevates the risk of HIV acquisition among young women, especially when it involves frequent exchanges of money and/or gifts. However, the effect was attenuatedafterthe main trial, possibly due to the changing nature oftransactionalsex and sexual partners as women age. These findings suggest that reducing transactional sex among young women, especially during adolescence, is important for HIV prevention.
dc.description.librarianPM2023
dc.identifier.urihttp://hdl.handle.net/10539/35886
dc.language.isoen
dc.titleTransactional sex and incident HIV infection in a cohort of young women from rural South Africa
dc.typeArticle
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