Anthropometric deficits and the associated risk of death by age and sex in children aged 6-59 months: A meta-analysis

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dc.contributor.authorSusan Thurstans
dc.contributor.authorStephanie V. Wrottesley
dc.contributor.authorBridget Fenn
dc.contributor.authorTanya Khara
dc.contributor.authorPaluku Bahwere
dc.contributor.authorJames A. Berkley
dc.contributor.authorRobert E. Black
dc.contributor.authorErin Boyd
dc.contributor.authorMichel Garenne
dc.contributor.authorSheila Isanaka
dc.contributor.authorNatasha Lelijveld
dc.contributor.authorChristine M. McDonald
dc.contributor.authorAndrew Mertens
dc.contributor.authorMartha Mwangome
dc.contributor.authorKieran S. O'Brien
dc.contributor.authorHeather Stobaugh
dc.contributor.authorSunita Taneja
dc.contributor.authorKeith P. West
dc.contributor.authorSaul Guerrero
dc.contributor.authorMarko Kerac
dc.contributor.authorAndré Briend
dc.contributor.authorMark Myatt
dc.date.accessioned2024-03-04T11:10:39Z
dc.date.available2024-03-04T11:10:39Z
dc.date.issued2023-08
dc.description.abstractRisk of death from undernutrition is thought to be higher in younger than in older children, but evidence is mixed. Research also demonstrates sex differences whereby boys have a higher prevalence of undernutrition than girls. This analysis described mortality risk associated with anthropometric deficits (wasting, underweight and stunting) in children 6-59 months by age and sex. We categorised children into younger (6-23 months) and older (24-59 months) age groups. Age and sex variations in near-term (within 6 months) mortality risk, associated with individual anthropometric deficits were assessed in a secondary analysis of multi-country cohort data. A random effects meta-analysis was performed. Data from seven low-or-middle-income-countries collected between 1977 and 2013 were analysed. One thousand twenty deaths were recorded for children with anthropometric deficits. Pooled meta-analysis estimates showed no differences by age in absolute mortality risk for wasting (RR 1.08, p = 0.826 for MUAC < 125 mm; RR 1.35, p = 0.272 for WHZ < -2). For underweight and stunting, absolute risk of death was higher in younger (RR 2.57, p < 0.001) compared with older children (RR 2.83, p < 0.001). For all deficits, there were no differences in mortality risk for girls compared with boys. There were no differences in the risk of mortality between younger and older wasted children, supporting continued inclusion of all children under-five in wasting treatment programmes. The risk of mortality associated with underweight and stunting was higher among younger children, suggesting that prevention programmes might be justified in focusing on younger children where resources are limited. There were no sex differences by age in mortality risk for all deficits.
dc.description.librarianPM2023
dc.facultyFaculty of Health Sciences
dc.identifier.urihttps://hdl.handle.net/10539/37752
dc.language.isoen
dc.schoolPublic Health
dc.subjectage; mortality; sex; stunting; underweight; wasting.
dc.titleAnthropometric deficits and the associated risk of death by age and sex in children aged 6-59 months: A meta-analysis
dc.typeArticle
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