Globin genes of the South African Indian population group.

dc.contributor.authorKrause, Amanda
dc.date.accessioned2018-12-19T09:19:20Z
dc.date.available2018-12-19T09:19:20Z
dc.date.issued1994
dc.descriptionA dissertation submitted to the Faculty of Medicine, University of tlie Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Pliilosophyen_ZA
dc.description.abstractMost South Africans with clinically significant haemoglobinopathies, mainly thalassaemia major, are of Asian Indian origin. This study was undertaken to characterise the normal and pathological variation around the a and B globin clusters, both at the haematological and molecular level in the major religious and language subgroups of South African Indians, These data were used to assess the need for a screening programme for the major haemoglobinopathies and to evaluate the local prenatal diagnostic service. The variation was also used to assess the genetic relationships between the subgroups of South African Indians, to compare them to Indians studied elsewhere and to other populations. (Abbreviation abstract)en_ZA
dc.description.librarianAndrew Chakane 2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/26228
dc.language.isoenen_ZA
dc.subjectHemaglobinopathies.en_ZA
dc.titleGlobin genes of the South African Indian population group.en_ZA
dc.typeThesisen_ZA
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