Faculty of Commerce, Law and Management (ETDs)
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Item Implication of Regulated Cannabis Legalisation on Wellbeing and Economic Growth(University of the Witwatersrand, Johannesburg, 2022) Quarshie, Emmanuel; Alagidede, Imhotep PaulThis is a thesis on the cost benefit analysis of cannabis legalisation, public (mis)perception about cannabis usage and cannabis users, the medical application of cannabinoids and their commercial and industrial potential in the new global political economy. The study shows that, although there are misconceptions about cannabis, there is still much to unpack about its effects on human well-being. Drawing on both qualitative and quantitative cross-country dataset from Ghana and South Africa, the study employed a logit model to address the following questions: (a) What does society know about cannabis and its industrial and medical applications? (b) What is the evidence-based scientific claims of cannabis regarding human well-being? (c) What are the existing gaps between perception and knowledge? Among the contributions, this study clarifies the often-misunderstood position of cannabis in society and illuminates the blind side of the role of cannabis as an economic enabler in the post pandemic world. More importantly, while some schools of thought project cannabis as a gateway drug to the infernal realm, this study provides evidenced based on real-time practical experience from well- informed and educated users. The study provides a model for regulated cannabis legalisation, a proper guide on value-added supply chain mechanism, and guiding principles to ensure the model functions properly, based on lessons and best practices from countries that have legalized cannabis, such as the Netherlands, Canada, Lesotho, Malawi, Zambia, South Africa, and Zimbabwe. This study further establishes empirical and theoretical foundations for the key thematic subjects of cannabis use, as well as a policy direction pertaining to its regulated legalisation, prohibition, or decriminalization in Ghana and South Africa. Given the disconnect between knowledge and perception about cannabis, the study recommended knowledge enhancement and adequate advocacy on the pros and cons of cannabis for society to enhance understanding of the benefits and its side effects to provide evidence-based guidance on the medical application and industrial potentialsItem Management factors contributing to delays in cancer drug registration in South Africa(University of the Witwatersrand, Johannesburg, 2022) Shai, Mmatsela LorraineOne of the leading causes of sickness and early death worldwide is cancer.The cancer mortality is especially high in low and middle-income countries (LMICs). The National Medicines Regulatory Authorities (NMRAs) play an important role to ensure that drugs meet the quality, safety, and efficacy requirements made available to patients. The National regulatory authorities are also accountable for enforcing regulatory demands promptly andensuring that patients have timely access to drugs. Delays in the registration of cancer drugs will have an adverse impact on cancer patients such as poor quality of life and early death. Section 27 of the Constitution of South Africa guarantees the right to have access to health care service. The study aims to determine management factors that contribute to delays in the registration of cancer drugs. As a result, the research contributes to the theoretical body of knowledge. The study took a qualitative approach by sending out an interview schedule to 10 South African pharmaceutical companies for self-completion. Several methods were considered in determining a suitable study strategy, study design, research approach, and self-administered interview questions. These methods were implemented in order to achieve the study’s objectives. This served as a primary source of information. The interview questions were completed and uploaded for analysis using the Qualtrics XM tool. The information that was gathered showed that all of the participants have to deal with the problem of registration delays for cancer drugs. The findings could help to clarify the overall critical factors, their impact, and the relationship between the key factors and stakeholders involved in cancer drug registration. The uniqueness of this research lies in the results provided by different participants from the pharmaceutical industry and in evaluating their perspectives on these delays. The research adds significant value through its evidence based on the responses received