3. Electronic Theses and Dissertations (ETDs) - All submissions
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Item Periprocedural myocardial infarction following percutaneous coronary intervention at Charlotte Maxeke Johannesburg Academic Hospital(2017) Tsabedze, Nqoba IsraelThe very first coronary artery balloon angioplasty is reported to have been performed by Gruntzig in 1977.1 Subsequently to this, over the past 40 years, there have been significant advances in coronary angiography and intervention. Coronary artery interventional techniques have evolved and improved significantly. There have been considerable device developments, new generation stents and novel antiplatelet therapy which have all proved to reduce the incidence of the primary periprocedural complications associated with percutaneous coronary intervention (PCI). [No abstract provided. Information taken from introduction]Item Serotonin antagonism in primate experimental myocardial infarction(1992-10-07) Hartford, Craig GordonSerotonin (5-Hydroxytryptamine, 5-HT) mediates vasoconstriction and vasodilation in the normal coronary circulation of various animal species. In the presence of coronary artery disease serotonin may inhibit coronary collateral formation and stimulate predominantly vasoconstriction. This study tested the effect of ketanserin, a selective 5-HT2 receptor antagonist and platelet aggregation inhibitor, on ischaemic myocardium blood flow and coronary collateral formation following coronary artery occlusion in primates.Item Expert opinions on best practice for the occupational therapy management of visual perceptual deficits in adults post stroke(2013) Reed, Bronwyn JoyVisual perceptual impairment is a common consequence of stroke which may affect all areas of occupational performance. The evidence for the management of these deficits in occupational therapy is not clear. The purpose of this qualitative study was therefore to determine the expert opinion for best practice in the management of visual perceptual deficits in adults post stroke in the South African context. Interviews with eight expert occupational therapists indicated that a lack of clarity exists in this area of clinical practice. Findings indicate this is a complex area of practice where management needs to be focussed on occupation based therapy for the individual patient in their context. The use of standardised and non-standardised assessments and compensation verses remediation in intervention must be individually determined, and the use of a “top down” approach was considered preferable. This study presents the first step in the development of clinical guidelines for management of this deficit in occupational therapy in South Africa.