Browsing by Author "Lisa Berkman"
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Item Apolipoprotein E Genetic Variation and Its Association With Cognitive Function in RuralDwelling Older South AfricansCassandra Soo; MT Farrell; Stephen Tollman; Lisa Berkman; Almut Nebel; Michele RamsayItem Child support grant expansion and cognitive function among women in rural South Africa Findings from a natural experiment in the HAALSI cohort(PUBLIC LIBRARY SCIENCE) R Chakraborty; Lindsay Kobayashi; J Jock; Cody Wing; E etal; Lisa Berkman; Kathleen Kahn; Chodziwadziwa Kabudula; Molly RosenbergItem Cohort Profile: Health and Ageing in Africa: A Longitudinal Study of an INDEPTH Community in South Africa (HAALSI).(2018) F Xavier Go´ mez-Olive´; Livia Montana; Ryan G Wagner; Chodziwadziwa W Kabudula; Julia K Rohr; Kathleen Kahn; Till Ba¨rnighausen; Mark Collinson; David Canning; Thomas Gaziano; Joshua A Salomon; Collin F Payne; Alisha Wad; Stephen M Tollman; Lisa BerkmanItem Effect of a cash transfer intervention on memory decline and dementia probability in older adults in rural South AfricaMolly Rosenberg; E Beidelman; X Chen; Chodziwadziwa Kabudula; Audrey Pettifor; D Bassil; Lisa Berkman; Kathleen Kahn; Stephen Tollman; Lindsay KobayashiItem Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community.(2023-03-27) Cassandra C. Soo; Jean-Tristan Brandenburg; Almut Nebel; Stephen Tollman; Lisa Berkman; Michèle Ramsay; Ananyo ChoudhuryCognitive function is an indicator for global physical and mental health, and cognitive impairment has been associated with poorer life outcomes and earlier mortality. A standard cognition test, adapted to a rural-dwelling African community, and the Oxford Cognition Screen-Plus were used to capture cognitive performance as five continuous traits (total cognition score, verbal episodic memory, executive function, language, and visuospatial ability) for 2,246 adults in this population of South Africans. A novel common variant, rs73485231, reached genome-wide significance for association with episodic memory using data for ~14 million markers imputed from the H3Africa genotyping array data. Windowbased replication of previously implicated variants and regions of interest support the discovery of African-specific associated variants despite the small population size and low allele frequency. This African genome-wide association study identifies suggestive associations with general cognition and domain-specific cognitive pathways and lays the groundwork for further genomic studies on cognition in Africa.Item Impact of family networks on uptake of health interventions: evidence from a community-randomized control trial aimed at increasing HIV testing in South Africa(INT AIDS SOCIETY) K Makofane; H-Y Kim; ET Tchetgen; MT Bassett; Lisa Berkman; E et al; B TillItem Impact of the South African Child Support Grant on memory decline and dementia probability in rural and lowincome mothers 20142021E T Beidelman; R Chakraborty; J Jock; Chodziwadziwa Kabudula; M L Phillips; E et al; Kathleen Kahn; Lisa Berkman; Lindsay Kobayashi; Molly RosenbergItem Telomere length, health, and mortality in a cohort of older black South African adultsS Gao; J Rohr; I de Vivo; Michele Ramsay; N Kriegler; Chodziwadziwa Kabudula; E et al; Lisa BerkmanItem The doubleedged role of accessed status on health and wellbeing among middle and olderage adults in rural South Africa The HAALSI studyS T Yu; Brian Houle; Lenore Manderson; E A Jennings; Stephen Tollman; Lisa Berkman; Guy HarlingItem TRENDS IN HOUSEHOLD MATERIAL RESOURCES AND COGNITIVE HEALTH IN A LONGITUDINAL COHORT STUDY OF AGING IN SOUTH AFRICA(2022) Lindsay Kobayashi; Chodziwadziwa Kabudula; Mohammed Kabeto; Xuexin Yu; Stephen Tollman; Kathleen Kahn; Lisa Berkman; Molly RosenbergMaterial resources that affect daily living conditions may be salient for cognitive aging in low-income settings, but evidence is limited on this topic. We investigated relationships between long-term trends in household material resources and subsequent cognitive function among 4,580 adults aged ≥40 in a population-representative cohort in Agincourt sub-district, South Africa, from 2001-2015. Household material resources (dwelling materials, water, sanitation, sources of power, modern amenities, and livestock) were assessed biennially from 2001- 2013. We evaluated mean resources, volatility in resources, and change in resources over this period in relation to cognitive function in 2014/2015. Higher mean household resources and larger improvements over time in resources were positively associated with subsequent cognitive function, independent of confounders. Findings were largely driven by modern amenities for food preparation, transportation, and communication outside of the household. Access to these amenities may support cognitive aging through boosting nutrition and cognitive reserve and should be investigated further.