Browsing by Author "Barry Jacobson"
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Item A case series of factor v leiden mutation in pregnancyJenique Bailly; Barry Jacobson; Susan LouwItem Profile of antiphospholipid antibodies in HIVinfected and HIVuninfected women with a history of thrombosisElise Schapkaitz; Elena Libhaber; Barry Jacobson; Annika Gerber; Haroun Rhemtula; H BullerItem Safety and Efficacy of Enoxaparin in Pregnancy A Systematic Review and MetaAnalysisBarry Jacobson; Virendra Rambiritch; Dara Paek; Tobias Sayre; Poobalan Naidoo; E et al.Item The Novel Coronavirus and Haemostatic abnormalities pathophysiology clinical manifesttations and treatment recommendationsSusan Louw; Barry Jacobson; Elizabeth Mayne; Tracey WiggillThe COVID-19 pandemic, caused by the SARS-C0V-2 virus, was initially considered and managed in a similar manner to the previous SARS epidemic as they are both caused by coronaviruses. What has now become apparent is that a major cause of morbidity and mortality in COVID-19 is abnormal thrombosis. This thrombosis occurs on a macro- and microvascular level and is unique to this disease. The virus has been demonstrated in the endothelium of the pulmonary alveoli and as such is thought to contribute to the devastating respiratory complications encountered. D-dimer concentrations are frequently raised in COVID to levels not frequently seen previously. The optimal anticoagulation treatment in COVID remains to be determined, and the myriad of pathophysiologic effects caused by this virus in the human host have also yet to be fully elucidated.Item von Willebrand factor propeptidetoantigen ratio in HIVinfected pregnancy Evidence of endothelial activationElise Schapkaitz; Elena Libhaber; Barry Jacobson; Muriel Meiring; Harry R Buller