Measurement of intraepidermal nerve fibre density in individuals with antiretroviral toxic neuropathy
dc.contributor.author | Patel, Imraan Goolam | |
dc.date.accessioned | 2014-02-11T13:13:21Z | |
dc.date.available | 2014-02-11T13:13:21Z | |
dc.date.issued | 2014-02-11 | |
dc.description | Dissertation submitted to the Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, in fulfillment of the requirements for the degree of Master of Science in Medicine, Johannesburg, 2011 | |
dc.description.abstract | HIV-associated sensory neuropathy (HIV-SN) is a common complication of HIV infection and its treatment with dideoxynucleoside drugs such as stavudine. Pain is a symptom in about 75% of cases of HIV-SN. The aim of this study was to set up the intraepidermal nerve fibre density (IENFD) quantification technique in a South African Laboratory and then to use this technique to investigate whether the presence of pain in individuals with HIV-associated sensory neuropathy was associated with the dying back of epidermal nerve fibres at the site at which pain was experienced. | en_ZA |
dc.identifier.uri | http://hdl.handle.net10539/13727 | |
dc.language.iso | en | en_ZA |
dc.subject.mesh | Antiretroviral Therapy, Highly Active | |
dc.subject.mesh | Nerve Fibers | |
dc.title | Measurement of intraepidermal nerve fibre density in individuals with antiretroviral toxic neuropathy | en_ZA |
dc.type | Thesis | en_ZA |