The generation of bone in nonhuman primates: experimental studies on the baboon

Abstract

Information concerning bone induction in primates is a prerequisite for the exploration of potential therapeutic applications for the regeneration of bone in humans Twenty-four recipient adult Chacma baboons (Papio ursinus) were used to study bone repair and regeneration initiated and promoted by osteoinductive and osteoconductive bo*'.e substitutes implanted in heterotopic intramuscular sites and in orthotopic calvarial sites.