Molecular methods to determine the presence of hepatitis B virus ( HBV ) genotypes in the serum of a hbv-infected chacma baboon

dc.contributor.authorNaicker., Tholsi. Jocelyn.
dc.date.accessioned2019-03-22T10:48:35Z
dc.date.available2019-03-22T10:48:35Z
dc.date.issued2004-03-17
dc.descriptionA research report submitted to the Faculty of Health Sciences, University of Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Medicine in the branch of Chemical Pathology. Johannesburg, 2004en_ZA
dc.description.abstractIn the course of a previous study (Kedda, et al., 2000), it became evident that the baboons had been inoculated with a mixture of HBV genotypes, namely, genotypes A and non-A. Therefore, a follow up study was undertaken to determine whether either A or non-A HBV genotypes predominated over the other during the time course of 52 weeks post-inoculation of HBV into baboons. HBV DNA extracted from sera obtained from one of the four HBV positive baboons, at two time points during a 52 week post-HBV inoculation period, was amplified using primers specific for the HBV core region that is well conserved in all genotypes.en_ZA
dc.description.librarianIT2019en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/26618
dc.language.isoenen_ZA
dc.subject.meshHepatitis B virus
dc.subject.meshDNA
dc.titleMolecular methods to determine the presence of hepatitis B virus ( HBV ) genotypes in the serum of a hbv-infected chacma baboonen_ZA
dc.typeThesisen_ZA
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