Genetic variation in gp 120 V1?V2 and neutralization sensitivity of HIV-1 subtype C isolates from children with rapid and slow disease progression

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dc.contributor.authorChoge, Isaac Ang' Ang' A
dc.date.accessioned2018-12-11T12:31:58Z
dc.date.available2018-12-11T12:31:58Z
dc.date.issued2003
dc.descriptiona dissertation submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg. for the Degree of Master of Science in Medicine (Virology) Johannesburg,. 2003en_ZA
dc.description.abstractThis project explore genetic variation and antibody neutralization sensitivity in gp 120 V1/V2 and C2-V5 region amongst HIV-1 subtype C pediatric isolates. Isolates from 25 slow progressing children and 16 rapid progressing infants were used in subtyping and quasispecies analysis performed with a novel V1/V2 heteroduplex mobility assay (HMA)en_ZA
dc.description.librarianIT2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/26210
dc.language.isoenen_ZA
dc.subject.meshHIV Envelope Protein gp120
dc.subject.meshHIV-1
dc.subject.meshChild
dc.subject.meshDNA
dc.titleGenetic variation in gp 120 V1?V2 and neutralization sensitivity of HIV-1 subtype C isolates from children with rapid and slow disease progressionen_ZA
dc.typeThesisen_ZA

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