Intermittent exsposure of gravid rats to 1% nitrous oxide and the effect on the postnatal growth of their offspring
dc.contributor.author | Viera, E | |
dc.contributor.author | Cleaton-Jones, P. E. | |
dc.contributor.author | Austin, J. | |
dc.contributor.author | et. al | |
dc.date.accessioned | 2015-12-15T13:04:51Z | |
dc.date.available | 2015-12-15T13:04:51Z | |
dc.date.issued | 1978-01 | |
dc.description | PK | en_ZA |
dc.description.abstract | Three groups of pregnant rats were exposed to 1% nitrous oxide 6 hours a day, 5 days per week for the first, first and second, and all 3 weeks of gestation. The offspring were weighed and measured at weekly intervals. The following variables were evaluated in control and experimental groups: litter size, body weight, tail length and body length. Litter sizes in animals exposed for the first and second weeks of gestation were significantly smaller than the controls. A two-way nested statistical analysis of the data revealed that over an 8-week period the experimental rats were significantly smaller than the control rats of the same age. Analysis of the 95% confidence intervals revealed no particular pattern related to the timing of the exposure to nitrous oxide. | en_ZA |
dc.identifier.citation | Viera, E., Cleaton-Jones, P. E., Austin, J., et al. 1978. Intermittent exsposure of gravid rats to 1% nitrous oxide and the effect on the postnatal growth of their offspring. SAMJ; 53: 106-108 | en_ZA |
dc.identifier.uri | http://hdl.handle.net/10539/19192 | |
dc.language.iso | en | en_ZA |
dc.subject | Nitrous Oxide/adverse effects | en_ZA |
dc.title | Intermittent exsposure of gravid rats to 1% nitrous oxide and the effect on the postnatal growth of their offspring | en_ZA |
dc.type | Article | en_ZA |