The synthesis and evaluation of BIS-1,2,3- triazolylidene(carbazolide) gold complexes as anticancer agents

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2021

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Van der Westhuizen, Danielle

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Abstract

Gold pincer complexes were evaluated for their potential as suitable anticancer agents. The use of a multidentate pincer ligand composed of an anionic carbazolide backbone and two flanking 1,2,3 triazol 5 ylidenes trz was proposed for the effective redox stabilization of the gold III complex under physiological conditions.

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A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Faculty of Science, School of Chemistry, University of the Witwatersrand, Johannesburg, 2021

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Van der Westhuizen, Danielle (2021) The synthesis and evaluation of bis-1,2,3-triazolylidene(carbazolide) gold complexes as anti-cancer agents, University of the Witwatersrand, Johannesburg, <http://hdl.handle.net/10539/32435>

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