Reticuloendothelial ferritin messenger RNA in inflammatory states

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dc.contributor.authorLapinsky, Stephen. E.
dc.date.accessioned2018-07-18T13:50:19Z
dc.date.available2018-07-18T13:50:19Z
dc.date.issued1989
dc.descriptionA dissertation submitted to the Faculty of Medicine University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the Degree Master of Science in Medicineen_ZA
dc.description.abstractFerritin is an iron storage protein, made up of heavy (H) and light (L) subunits. Ferritin synthesis is regulated at a post transcriptional level by iron, which induces a redistribution of ferritin mRNA from a free cytoplasmic pool to polyribosomes. Inflammatory states influence iron metabolism, causing a decrease in serum iron levels associated with an increase in reticuloendothelial ferritin synthesis and iron storage.en_ZA
dc.description.librarianIT2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/25046
dc.language.isoenen_ZA
dc.subject.meshRNA
dc.subject.meshFerritins
dc.subject.meshIron
dc.subject.meshMetabolism
dc.titleReticuloendothelial ferritin messenger RNA in inflammatory statesen_ZA
dc.typeThesisen_ZA
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