Reticuloendothelial ferritin messenger RNA in inflammatory states
| dc.contributor.author | Lapinsky, Stephen. E. | |
| dc.date.accessioned | 2018-07-18T13:50:19Z | |
| dc.date.available | 2018-07-18T13:50:19Z | |
| dc.date.issued | 1989 | |
| dc.description | A dissertation submitted to the Faculty of Medicine University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the Degree Master of Science in Medicine | en_ZA |
| dc.description.abstract | Ferritin is an iron storage protein, made up of heavy (H) and light (L) subunits. Ferritin synthesis is regulated at a post transcriptional level by iron, which induces a redistribution of ferritin mRNA from a free cytoplasmic pool to polyribosomes. Inflammatory states influence iron metabolism, causing a decrease in serum iron levels associated with an increase in reticuloendothelial ferritin synthesis and iron storage. | en_ZA |
| dc.description.librarian | IT2018 | en_ZA |
| dc.identifier.uri | https://hdl.handle.net/10539/25046 | |
| dc.language.iso | en | en_ZA |
| dc.subject.mesh | RNA | |
| dc.subject.mesh | Ferritins | |
| dc.subject.mesh | Iron | |
| dc.subject.mesh | Metabolism | |
| dc.title | Reticuloendothelial ferritin messenger RNA in inflammatory states | en_ZA |
| dc.type | Thesis | en_ZA |