Anastrozole when used as a superovulator, may alter key focal adhesion proteins associated with receptivity of uterine epithelial cells during implantation in the rat: a potential therapeutic clue in assisted reproductive technologies

Abstract

Introduction: Anastrozole is clinically effective in ovulation induction, but it has not been well researched. The aim of this study was to determine the optimal dose for anastrozole as a superovulator and ascertain its effects on implantation in Wistar rats; also to determine its effects on uterine morphology during early pregnancy using light microscopy and scanning electron microscopy (SEM). [Abbreviated Abstract. Open document to view full version]