Anastrozole when used as a superovulator, may alter key focal adhesion proteins associated with receptivity of uterine epithelial cells during implantation in the rat: a potential therapeutic clue in assisted reproductive technologies
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Date
2015
Authors
Mwakikunga, Anthony Raphael.
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Abstract
Introduction: Anastrozole is clinically effective in ovulation induction, but it has not been well researched. The aim of this study was to determine the optimal dose for anastrozole as a superovulator and ascertain its effects on implantation in Wistar rats; also to determine its effects on uterine morphology during early pregnancy using light microscopy and scanning electron microscopy (SEM). [Abbreviated Abstract. Open document to view full version]
Description
A thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfillment of the requirements for the degree of Doctor of Philosophy
July, 2015
Keywords
Anastrozole, Superovulator, Receptivity of uterine, Epithelial cells, Implantation, Reproductive technologies