Antibiotic resistance in viridans streptococci

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dc.contributor.authorPotgieter, Elsa
dc.date.accessioned2019-02-15T12:00:48Z
dc.date.available2019-02-15T12:00:48Z
dc.date.issued1994
dc.descriptionA thesis submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements of Doctor of Philosophy. Johannesburg 1994en_ZA
dc.description.abstractViridans streptococci are aetiological agents of endocarditis, bacteraemia, dental caries and abscesses of the liver, brain and joints. Viridans streptococci had until recently generally been considered to be uniformly susceptible to antimicrobial agents active against Gram-positive cocci. The susceptibility of 211 viridans streptococci isolated from blood in South Africa between 1988-1991 to eight antimicrobial agents was determined. Thirty-eight percent of the isolates were found to be resistant to penicillin (MICs >0.25 /Mg/ml). Five Streptococcus mitis isolates exhibited increased (MIC 64 and 128 ^g/ml) or high-level (MIC >500 /Mg/ml) resistance to gentamicin. In vitro synergy between penicillin and gentamicin was not demonstrated with these isolates.en_ZA
dc.description.librarianIT2019en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/26439
dc.language.isoenen_ZA
dc.subject.meshDrug Resistance, Microbial
dc.subject.meshViridans Streptococci
dc.subject.meshEndocarditis
dc.subject.meshBacteremia
dc.subject.meshGram-Positive Cocci
dc.titleAntibiotic resistance in viridans streptococcien_ZA
dc.typeThesisen_ZA
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