GIFT AND ZIFT: Is there a place for these procedures in a new era of assisted reproduction?
| dc.contributor.author | De Jongh, Skye Francis | |
| dc.date.accessioned | 2021-12-15T01:47:20Z | |
| dc.date.available | 2021-12-15T01:47:20Z | |
| dc.date.issued | 2021 | |
| dc.description | A research reported submitted to the University of the Witwatersrand, Faculty of Health Sciences, in partial fulfilment of the degree of Master of Medicine in Obstetrics and Gynaecology, 2021 | en_ZA |
| dc.description.abstract | The aim of this study is to document the incidence of successful pregnancy following gamete intra-fallopian tube transfer (GIFT) and zygote intra-fallopian transfer (ZIFT). It is a descriptive, retrospective study that took place at Vitalab Center for Assisted Conception in South Africa. Sixty three patients who underwent GIFT or ZIFT between January 2015 and March 2017 were included in the study. Each patient either underwent a GIFT or a ZIFT depending on their individual circumstances. The main outcome measures were; biochemical pregnancy, clinical pregnancy, miscarriage or ectopic pregnancy. The combined biochemical pregnancy success rate was 42.9% with a clinical pregnancy success rate of 29%. Interestingly, 50% of the subjects who previously had 100% aneuploidy, had biochemical pregnancies and 33% had successful clinical pregnancies. In conclusion, although GIFT and ZIFT exhibited a clinical pregnancy success rate of 33% versus the overall success rate of IVF of 58% at Vitalab in 2016, these techniques should be considered as options in those who have previously failed conventional IVF or ICSI more than twice. GIFT and ZIFT may also be considered in patients with recurrent 100% aneuploidy on PGS. Further research is needed to understand how one third of the patients who previously exhibited recurrent aneuploid embryos, achieved successful clinical pregnancies post GIFT and ZIFT | en_ZA |
| dc.description.librarian | CK | en_ZA |
| dc.faculty | Faculty of Health Sciences | en_ZA |
| dc.identifier.uri | https://hdl.handle.net/10539/32322 | |
| dc.language.iso | en | en_ZA |
| dc.title | GIFT AND ZIFT: Is there a place for these procedures in a new era of assisted reproduction? | en_ZA |
| dc.type | Thesis | en_ZA |