A preformulation study of pyridoxal hydrochloride for solid dosage form desigh and development

dc.contributor.author	Durig, Thomas.
dc.date.accessioned	2018-11-20T07:56:53Z
dc.date.available	2018-11-20T07:56:53Z
dc.date.issued	1991-08
dc.description	A Dissertation Submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg for the Degree of Master of Pharmacy. Johannesburg, August 1991	en_ZA
dc.description.abstract	In this dissertation physicochemical properties of the Bs vitamer, pyridoxal hydrochloride (PL HC1), are investigated with the aim of generating the necessary profile for the rational development of a stable, safe and effective formulation containing this drug. Recent research suggests that administration of PL HC1 may be particularly effective in raising the depleted intracellular pyridoxal phosphate levels found in many asthmatics treated with theophylline. The solubility characteristics of PL HC1 suggest that its absorption and bioavailability should not be problematic	en_ZA
dc.description.librarian	IT2018	en_ZA
dc.identifier.uri	https://hdl.handle.net/10539/26090
dc.language.iso	en	en_ZA
dc.subject.mesh	Pyridoxal
dc.subject.mesh	Chemical Phenomena
dc.subject.mesh	Theophylline
dc.title	A preformulation study of pyridoxal hydrochloride for solid dosage form desigh and development	en_ZA
dc.type	Thesis	en_ZA

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