An open label, multicentre study of topiramate (topamax) as adjuctive therapy in patients with partial onset seizures with or without secondary generalisation, that are inadequately controlled

Abstract

Topiramate is an effective adjuctive anticonvulsant with a favourable safety profile. Topiramate is a sulphamate-substituted monosaccharide derived from D-fructose and is structurally unrelated to other anti-epileptic drugs .It is available in variable strength, tablet and sprinkle capsule formulations. It acts by multiple mechanisms that suggest it may be effective in sevsral types of epilepsy