The role of the conserved ASP443 and ASP498 residues in the polymerase and RNase H activities of HIV-1 reverse transcriptase
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Date
1993
Authors
Brooksbank, Richard L
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Abstract
The roles of the highly conserved aspartic acid residues found at positions 443 and 498 within the RNase H domain of Human Immunodeficiency Virus type-1 reverse transcription were investigated by the defined substitution of these residues using site-directed
mutagenesis.
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Description
Submiltted in fulfillment of
the requirements for the
degree of Master of Science in
the faculty of Science,
University of the Witwatersrand,
Johannesburg •
Johannesburg 1993.
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Citation
Brooksbank, Richard L. (1993) The role of the conserved ASP443 and ASP498 residues in the polymerase and RNase H activities of HIV-1 reverse transcriptase, University of the Witwatersrand, Johannesburg, <http://wiredspace.wits.ac.za/handle/10539/21434>