Preformulation and formulation study of dexchlorphenniramine maleate for use in the development of a new sustained release dosage form

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dc.contributor.authorFabian, June
dc.date.accessioned2018-11-06T13:57:47Z
dc.date.available2018-11-06T13:57:47Z
dc.date.issued1994-03
dc.descriptionA Dissertation Submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in Partial Fulfilment of the Requirements for the Degree of Master of Pharmacy Johannesburg, March 1994en_ZA
dc.description.abstractPreformulation and formulation study of dexchlor- pheniramine maleate (DCPM) for it's inclusion into a gelforming sustained release dosage form was investigated. A modification of the USP apparatus 2 is proposed as an alternative to currently recommended USP dissolution apparatus for floating, gelforming drug delivery systems. In addition, the role of magnesium stearate and talc as dissolution retardants in controlled release matrix tablets is investigated, through application of a factorial design.en_ZA
dc.description.librarianIT2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/25978
dc.language.isoenen_ZA
dc.subject.meshdexchlorpheniramine
dc.subject.meshCalorimetry, Differential Scanning
dc.subject.meshChromatography
dc.subject.meshChromatography, High Pressure Liquid
dc.subject.meshSpectrophotometry, Ultraviolet
dc.titlePreformulation and formulation study of dexchlorphenniramine maleate for use in the development of a new sustained release dosage formen_ZA
dc.typeThesisen_ZA
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