The in vitro activity of antimicrobial agents alone and in combination against clinical isolates of gram-positive bacteria

Abstract

Analysis of organisms involved in hospital infections has shown that Gram -positive bacteria have assumed an increasingly important role. Examples that have been recognised as important pathogens are staphylococci,enterococci, streptococci, Corynebacterium jeikeium and Leuconostoc species. Methicillin resistance in staphylococci has become a major problem in certain hospitals. Viridans streptococci continue to be the most frequent cause of native valve endocarditis. Leuconostoc species are being increasingly isolated from blood culture specimens.