The use of technetium 99m hexa-methyl propylene amine oxime spect scanning in acute stroke management.
Date
1991
Authors
Winterton, Ruth
Journal Title
Journal ISSN
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Abstract
19 patients were selected, from the patients screened, for investigation
within 48 hours of the onset of an ischaemic cerebrovascular accident.
Clinical neurulogical scoring, computerized tomography lCT) scans and
single photon emission computed tomography (SPECT) scans were performed
on day 1, day 10 and day 30.
SPECT scan data was analysed by 5 semi-quantitative methods, and
findings were compared with neuroloyical clinical scores on each
respective day.
It was found that day 1 SPECT scans are of value for early localization
of the acute ischaemic infarction.
A multiple regression model was developed using both the day 30 Defect
Volume index and segmental analysis score which related to the day 30
clinical scores. The day 1 model was unsatisfactory and no such model
was found relating day 10 SPECT semi-quantitative methods to day 10
clinical scoring. Changes in semi-quantitative scores from day 1 to day
30 did not correlate with clinical changes. Longer follow up may be
required for there to be value in performing SPECT scans in stroke
trials.
A prognostic equation was derived by multiple regression analysis of day
1 SPECT scan scores and day 30 clinical scores.
Description
A short report submitted to the Faculty of Medicine,
University of the Witwatersrand in partial fulfilment of the
requirements for the degree of Master of Medicine in Nuclear
Medicine
Keywords
Tomography, Emission-Computed, Single-Photon., Cerebrovascular Disorders radiography.