The incidence of executive cognitive dysfunction detected by a bedside executive screening tool (BEST) in a cohort of type 2 diabetes attending a tertiary diabetic clinic

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dc.contributor.authorDe Wet, Hayley Beryl
dc.date.accessioned2011-02-24T09:00:41Z
dc.date.available2011-02-24T09:00:41Z
dc.date.issued2011-02-24
dc.descriptionMMed, Internal Medicine, Faculty of Health Sciences,University of the Witwatersranden_US
dc.description.abstractAims: To determine whether impairment of the executive functioning domain of cognition could be detected by a battery of simple bedside cognitive tests of executive function associated with inadequate glycaemic control. Methods: People with type 2 diabetes attending a tertiary referral diabetic clinic who consented to participate in the study underwent a brief battery of cognitive testing (the Bedside Executive Screening Test) designed to detect executive function impairment. Glycaemic control was determined using glycated haemoglobin levels (HbA1c). Inadequate glycaemic control was defined as HbA1c ≥ 7.0%. Results: Executive function impairment was detected in 51 (52%) of the 98 study participants. The presence of executive function impairment was significantly associated with poor glycaemic control (HbA1c ≥ 7.0%) (odds ratio 4.9, 95% confidence interval 1.3 – 18.8, p=0.019). There were no significant differences between patients with and without executive function impairment with regard to age, target organ damage, patient reported adherence, and hypoglycaemic therapy. Patients with a lower level of education were more likely to demonstrate executive impairment when glycaemic control was poor (p=0.013). Conclusion: Executive function impairment is common in a population of people with difficult-to-manage type 2 diabetes. The presence of executive impairment is significantly associated with poor glycaemic control.en_US
dc.identifier.urihttp://hdl.handle.net/10539/9086
dc.language.isoenen_US
dc.subjecttype 2 diabetesen_US
dc.subjecttype 2 diabeticsen_US
dc.subjectcognitive dysfunctionen_US
dc.titleThe incidence of executive cognitive dysfunction detected by a bedside executive screening tool (BEST) in a cohort of type 2 diabetes attending a tertiary diabetic clinicen_US
dc.typeThesisen_US
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