The in-vitro effect of ridogrel on platelet function in normocholesterolaemic subjects and familial hypercholesterolaemic subjects

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dc.contributor.authorNaran, Nitien, Hira.
dc.date.accessioned2018-05-17T08:07:07Z
dc.date.available2018-05-17T08:07:07Z
dc.date.issued1996-03
dc.descriptionA dissertation submitted to the Faculty of Medicine University of the Witwatersrand, Johannesburg, for the Degree of Master of Scienceen_ZA
dc.description.abstractFamilial hypercholesterolaemia IIa (F. H. IIA) is a congenital disorder characterized by a raised plasma level of low density lipoprotein (LDL). Platelets in this condition have been found to be hypersensitive to aggregating agents and to produce increased amounts of thromboxane A2.These modifications of platelet function and biochemistry may play an important role in the occurrence of premature atherosclerosis and myocardial infarction in adolescence and young adults.en_ZA
dc.description.librarianIT2018en_ZA
dc.identifier.urihttps://hdl.handle.net/10539/24488
dc.subject.meshIn Vitro Techniques
dc.subject.meshBlood Platelets
dc.subject.meshPlatelets Function tests
dc.subject.meshHypercholesterolemia
dc.subject.meshLipoproteins, LDL
dc.subject.meshAtherosclerosis
dc.titleThe in-vitro effect of ridogrel on platelet function in normocholesterolaemic subjects and familial hypercholesterolaemic subjectsen_ZA
dc.typeThesisen_ZA
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