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Author: search.filters.author.Muhammad, NasiruSubject: search.filters.subject.male rats

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    Moringa Study (20151151B)
    (2020-12-15) Muhammad, Nasiru; Ibrahim, Kasimu Ghandi; Ndhlala, Ashwell; Erlwanger, Kennedy; Erlwanger, Kennedy
    Cleaned data from the experiement conducted with 21-day old male Sprague-Dawley rats . These rats(n=50) were randomized to six treatment groups (n=8-9) with unlimited access to commercial rat feed. Either plain water (C) or 20% fructose solution (Fr) were provided to drink. 400 mg.kg-1 M. oleifera methanolic leaf extract (Mo) or 100 mg.kg-1 fenofibrate were also administered daily for ten weeks. Growth, circulating metabolites, visceral and epididymal fat pads mass, hepatic lipids and general health markers were assessed. Liver samples were histologically examined using H&E stain. Analysis of the data was done with GraphPad Prism 5.0v for windows (GraphPad Software, Inc. CA), and the data were expressed as mean ± standard deviation and analysed by means of a one-way analysis of variance (ANOVA). Statistical significance was considered at P < 0.05.