2. Academic Wits University Research Outputs (All submissions)
Permanent URI for this communityhttps://hdl.handle.net/10539/36826
Browse
Search Results
Item Derangements of immunological proteins in HIVassociated diffuse large Bcell lymphoma the frequency and prognostic impact(FRONTIERS RESEARCH FOUNDATION) Jenifer Vaughan; Mohammed Patel; Melinda Suchard; Maemu Gededzha; Heena Ranchod; Wayne Howard; T Snyman; Tracey WiggillItem Extranodal presentation of a lymphoma with precursor Bcell phenotype and translocation t814 in South AfricaKatherine Hodkinson; Yvonne Perner; Deborah Glencross; Tracey Wiggill; Adam Botha; Janet PooleItem The translocation t119q23p13 TCF3PBX1 fusion is the most common recurrent genetic abnormality detected amongst patients with Bcell lymphoblastic leukaemia in Johannesburg South AfricaJenifer Vaughan; Nikki Bouwer; Pascale Willem; Tracey Wiggill; Katherine HodkinsonItem The Novel Coronavirus and Haemostatic abnormalities pathophysiology clinical manifesttations and treatment recommendationsSusan Louw; Barry Jacobson; Elizabeth Mayne; Tracey WiggillThe COVID-19 pandemic, caused by the SARS-C0V-2 virus, was initially considered and managed in a similar manner to the previous SARS epidemic as they are both caused by coronaviruses. What has now become apparent is that a major cause of morbidity and mortality in COVID-19 is abnormal thrombosis. This thrombosis occurs on a macro- and microvascular level and is unique to this disease. The virus has been demonstrated in the endothelium of the pulmonary alveoli and as such is thought to contribute to the devastating respiratory complications encountered. D-dimer concentrations are frequently raised in COVID to levels not frequently seen previously. The optimal anticoagulation treatment in COVID remains to be determined, and the myriad of pathophysiologic effects caused by this virus in the human host have also yet to be fully elucidated.