3. Electronic Theses and Dissertations (ETDs) - All submissions

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End date: 1979Subject: search.filters.subject.Iron

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    Iron storage in the neonatal period of the human infant
    (1950) Van Dongen, L. G. R.
    Iron is one of the vital elements of the human body. Without it respiration would be quite impossible. Haemoglobin, the transporter of oxygen throughout the body, has iron as an essential constituent, and it is in this protein complex that the greatest bulk of the metal is found. Iron also plays a very essential part in the respiration of the tissues, as it is a vital element in intracellular respiratory enzymes such as catalase, cytochrome, cytochrome oxidase, etc. Further it is found in the chromatin material of nuclei in the cells of all the tissues.
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    The role of ferritin in iron absorption
    (1967-01) Torrance, J. D.
    Although reports of the medicinal use of iron date back to ancient times it was not until the present century that the many functions of iron in the body were studied. Once started, the investigation received impetus from the seriousness of iron deficiency anaemia, a major cause of ill health throughout the world. The introduction of radio-isotope tracer techniques in 1939 greatly facilitated investigation of absorption, excretion and the metabolic pathways of iron. The tremendous amount of work already carried out has led to a fairly comprehensive knowledge of the various aspects of iron metabolism. Nevertheless, there remain wide gaps in the overall picture. In
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    Factors involved in the handling of iron by the reticulo-endothelial system
    (1972) Lipschitz, D. A.
    For centuries iron was regarded as a source of health and vigour, and it has been known for at least 200 years that it is a component of blood and effective in the treatment of chlorosis. However, its metabolism remained largely a mystery until the advent of radioactive iron isotopes in 1938. Since then most of the major pathways of this metal into, through and out of the body have been elucidated. In addition the functions which it subserves have been partially characterized.
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    An in vivo and in vitro study of some luminal and cellular factors influencing iron absorption
    (1966-03) Jacobs, Peter
    Although the various factors which influence the absorption of iron from the gastrointestinal tract have been extensively investigated, there still remains uncertainty concerning several basic aspects of this process
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    Body iron excretion
    (1975-05-19) Green, Ralph
    An attempt was made to document iron losses from the body as a whole, as well as from individual excretory routes using a combination of radioisotopic and chemical techniques. The purpose of this work was to gain a better understanding of external body exchange, and to resolve some of the existing controversies regarding the magnitude of daily iron losses. The basis for this controversy is extensively reviewed in the thesis
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    Radioiron absorption studies in idiopathic haemochromatosis, malnutritional cytosiderosis, and transfusional haemosiderosis
    (1953-05) Bothwell, T. H.
    The quantity of iron in the body is regulated largely by the amount absorbed from the gut as the body's capacity to excrete it seems to be very limited. However three conditions have been described in which enormous amounts of iron may accumulate. Such a finding is characteristic of idiopathic haemochromatosis, it is present in a proportion of malnourished South African and is seen also in cases of refractory anaemia treated over long periods with blood transfusions.
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    Some physiological aspects of iron transport - studies on the fortification of sugar with iron
    (1976) Disler, Peter, Barry
    An attempt was made to fortify sugar with iron in order to prevent the development of iron deficiency. It was possible to add various iron salts and ascorbic acid to sugar without discolouring the vehicle even after storage for many months under hot humid conditions. The absorption of iron from fortified sugar and cereal meals was then measured in human volunteers using either an "extrinsic tag" to label the iron compound or intrinsically labelled food iron.
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