3. Electronic Theses and Dissertations (ETDs) - All submissions

Browse

Now showing 1 - 2 of 2

Iron Metabolism: a series of publications on various aspects of iron metabolism.
(1964-10) Bothwell, T. H.
ffiy interest in iron metabolism was initially aroused in 1948 by a young patient with idiopathic haemochromatosis who was admitted to Professor Elliott*© ward while I was serving my medical internship, With the support of the Council for Scientific and Industrial Research it was possible to carry out radioisotopic studies on this patient and over the next four years a number of other subjects with the same disease ware investigated. As the study continued, attention was also directed to the siderosis which is so common in adult Bantu, and to the Iron overload which results from the administration of repeated blood transfusions to subjects with refractory anaemias.
Radioiron absorption studies in idiopathic haemochromatosis, malnutritional cytosiderosis, and transfusional haemosiderosis
(1953-05) Bothwell, T. H.
The quantity of iron in the body is regulated largely by the amount absorbed from the gut as the body's capacity to excrete it seems to be very limited. However three conditions have been described in which enormous amounts of iron may accumulate. Such a finding is characteristic of idiopathic haemochromatosis, it is present in a proportion of malnourished South African and is seen also in cases of refractory anaemia treated over long periods with blood transfusions.