School of Oral Health Sciences

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    A comparative sem study of keratinized and non-keratinized oral mucosa of the vervet monkey
    (1981) Grossman, E. S.; Cleaton-Jones, P. E.
    Scanning electron microscopy has revealed that the surfaces of keratinized and non-keratinized oral epithelial cells have characteristic features which enable these tissue types to be readily distinguished. These features include pits, villus-like projections and ridge-like folds called microplications. The origin and functional significance of these structures is not known, although several hypotheses have been proposed. Microplications have been interpreted as a reserve area for cell stretching but further studies have yielded conflicting results. Cellular interdigitation resulting from the microplications may aid adhesion between the stratified epithelial cells. This view has been supported by subsequent investigations of superficial epithelial cells. The situation in the deeper cell layers is not entirely clear.
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    Ultrastructural features of exfoliating surface cells in keratinised and non-keratinised oral mucosa
    (1979) Austin, J. C.; Grossman, E. S.; Cleaton-Jones, P.
    Healthy keratinised and non-keratinised oral mucosa (attached gingiva and alveolar mucosa) were obtained from 6 adult vervet monkeys, fixed in situ by simultaneous perfusion and immersion fixation using cacodylate buffered 2,5% glutaraldehyde and prepared for examination by SEM and TEM.
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    General problems encountered by the postgraduate first-time electron microscopist
    (1988-10) Grossman, E. S.
    This article identifies the main problems encountered by the postgraduate first- time electron microscopist. Areas where difficulties arise occurred in the communication and planning of the project, general specimen preparation, safety in the laboratory, and in the use of the electron microscope facility. It is recommended that all students who wish to use the electron microscope as a research tool should attend a short course in EM organised by the EM unit staff in conjunction with the various academic departments whose students make use of the facility, before embarking on their research topic.