School of Oral Health Sciences
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Item How to set about a research project(1986) Cleaton-Jones, P.Item Writing a research report, dissertation or thesis(1986) Cleaton-Jones, P.Item Social class and dental caries in 11-12-year-old South African schoolchildren(1989) Cleaton-Jones, P.; Hargreaves, J. A.; Williams, S. D. L.; et al.The objective of this study was to examine effects of social class on dental caries in five African populations. Definitions of social class that could be used for the different ethnic groups are outlined. A total of 1 154 children from rural black, urban black, urban Indian, urban coloured and urban white groups were clinically examined and classified into social class by parental occupations. Within group comparisons showed no statistically significant differences in DMFT or DMFS scores by social class. Comparison of the urban white children to a similar group in South Wales showed slightly lower caries in South African children of similar social class. The complexity of the different ethnic groups in South Africa, in respect of social classification, is difficult to assess for comparison with social systems in developed countries. It is recommended that an appropriate social classification be developed for South Africa ’s developed/developing population mixture. Also as we enter the 1990’s sound baseline caries data need to be collected for longitudinal evaluation of changes in the disease patternItem Intercellular junctions in the attached gingiva and alveolar mucosa in the vervet monkey (cercopithecus aethiops)(1979) Grossman, E. S.; Austin, J. C.; Cleaton-Jones, P.This study was undertaken to determine the distribution of hemidesmosomes on the basal cell membranes adjacent to the basement lamina and the spinous cell membranes on unloaded keratinized AG and non- keratinized AM.Item Ultrastructural features of exfoliating surface cells in keratinised and non-keratinised oral mucosa(1979) Austin, J. C.; Grossman, E. S.; Cleaton-Jones, P.Healthy keratinised and non-keratinised oral mucosa (attached gingiva and alveolar mucosa) were obtained from 6 adult vervet monkeys, fixed in situ by simultaneous perfusion and immersion fixation using cacodylate buffered 2,5% glutaraldehyde and prepared for examination by SEM and TEM.Item Depth and area of dental erosions, and dental caries, in bulimic women(Sage Pub, 1989) Jones, R. R. H.; Cleaton-Jones, P.Dental caries and the severity (depth) and area of erosions of tooth substance were studied in 11 bulimic subjects and 22 matched controls. Erosions were seen in 69% of the bulimics' teeth and in only 7% of the controls' (p less than 0.001). Depth of penetration was greater in the bulimics, extending even into the pulp, and the area of erosion was also larger. Scores for dental caries were higher in bulimics (mean DMFS 27.9, median 36) than in controls (mean DMFS 19.1, median 13.5), although the difference was not statistically significant. This study suggests that when erosions are present on the lingual surfaces of maxillary anterior teeth, as well as on the buccal surfaces of maxillary canines, premolars, and maxillary incisors, a diagnosis of bulimia is likely. Patients with these signs should be referred for medical help.Item Zinc oxide-eugenol and calcium hydroxide pulpectomies in baboon primary molars: histological responses(2004) Cleaton-Jones, P.; Duggal, M.; Parak, R.; et alAIM: To compare histological responses to zinc oxide-eugenol (ZOE) and calcium hydroxide (CH) pulpectomies in primary molar teeth with inflamed pulps. STUDY DESIGN:This was an experimental study in 17 juvenile baboons (Papio ursinus). METHODS: Pulpitis was induced with fresh human carious dentine or Streptococcus mutans placed into occlusal cavities in 78 primary molars; after 14 days a pulpectomy was performed on the same primary molars with the two root fillings randomly allocated. The root canal openings were then covered with IRM and the cavity filled with amalgam. After 90 days specimens were harvested and examined under the light microscope with the examiner blind to the treatment. RESULTS:Reaction frequencies in the ZOE-treated versus CH-treated teeth were: no recognisable pulp 89% and 82%, internal root resorption 0% and 1%, external root resorption 11% and 24%, presence of bacteria 5% and 18%, periapical abscesses 24% and 52%. STATISTICS:Fisher's exact probability test showed a statistically significant higher prevalence of periapical abscesses in the CH-treated group (P=0.03, relative risk 2.2). CONCLUSIONS: ZOE pulpectomy is preferred to CH for the treatment of infected pulps in primary molarsItem Mitotic activity in the oral epithelium of the albino rat(1976) Cleaton-Jones, P.In groups of Wistar rats 3 and 12 months of age, colchicine and radioautography were used to assess mitotic activity in oral epitheliums. Apparent mitotic activity in the epitheliums of the cheek, hard palate, and central, intermediate, and lateral zones of the soft palate depended on the method used and the age of the rat.Item Radioautographic study of mesenchymal cell activity in the secondary palate of the rat(1976) Cleaton-Jones, P.Fifteen µCi of ³H-thymidine was injected into the amniotic cavity of fetal rats from day 15 to 19 postinsemination. Analysis of radioautographs from these rats did not show increased mesenchymal cell activity to be responsible for medial rotation of the palatal shelves. Variations in cell activity in the older fetuses were mainly due to developing bone and glands.Item Ferric sulphate and formocresol pulpotomies in baboon primary molars: histological responses(2002) Cleaton-Jones, P.; Duggal, M.; Parak, R.; Et alAim: To compare pulpal reactions to ferric sulphate and formocresol pulpotomies in primary molar teeth with inflamed pulps. Study design: An experimental study in 15 juvenile baboons (Papio ursinus). Materials and methods: Pulpitis was induced with fresh human carious dentine or Streptococcus mutans placed into occlusal cavities in 57 primary molars; after 14 days a pulpotomy was performed on the same primary molars with the two pulp medicaments randomly allocated; the pulp was covered with IRM and the cavity filled with amalgam. After 90 days specimens were harvested and examined under the light microscope with the examiner blind to the treatment. Results: Reaction frequencies in the ferric sulphate-treated and formocresol-treated teeth were: recognisable pulp 52% and 50%, dentine bridges 16% and 12%, internal root resorption 12% and 4%, external resorption 28% and 31%, bacteria 12% and 23%, peri-apical abscesses 32% and 38%. Statistics: Fisher’s exact probability test showed no statistically significant differences between reaction frequencies in the two treatment groups. Conclusion: A pulpotomy in a primary tooth may be clinically successful in the presence of adverse histological reactions.