Research Outputs (Clinical Medicine)
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Browsing Research Outputs (Clinical Medicine) by Department "Infectious Diseases"
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Item Making the case for an obstetric medicine subspecialty in South Africa(Health & Medical Publishing Group, 2020-11) Zamparini, J; Wium, LObstetric medicine is a subspecialty of internal medicine that involves the management of medical conditions that may affect the course of pregnancy. It is an established subspecialty in many parts of the world, with recognised training programmes and an active international society; however, no formal training programme has been developed in South Africa (SA) as yet. Medical problems are responsible for the majority (60%) of maternal deaths in SA and women of childbearing potential are disproportionately affected by medical conditions such as HIV and obesity. Obstetric physicians would play a complementary role in the care of pregnant patients and could contribute to improving maternal health and lowering the maternal mortality rate in SAItem Management of HIV-associated cryptococcal disease in South Africa(2014-12) Govender, N.P; Dlamini, SItem Successfully controlling malaria in South Africa(2014-03) Blumberg, I; Frean, J; Moonasar, DFollowing major successes in malaria control over the past 75 years, South Africa is now embarking on a malaria elimination campaign with the goal of zero local transmission by the year 2018. The key control elements have been intensive vector control, primarily through indoor residual spraying, case management based on parasitological diagnosis using evidence-based drug policies with artemisinin-based combination therapy since 2001, active health promotion in partnership with communities living in the malaria transmission areas, and cross-border collaborations. Political commitment and long-term funding for the malaria control programme have been a critical component of the programme’s success. Breaking the cycle of transmission through strengthening of active surveillance using sensitive molecular tests and field treatment of asymptomatic persons, monitoring for antimalarial drug resistance and insecticide resistance, strengthening cross-border initiatives, and ongoing programme advocacy in the face of a significant decrease in disease burden are key priorities for achieving the elimination goal.Item The predicted risk of adverse pregnancy outcomes as a result of treatmentassociated obesity in a hypothetical population receiving tenofovir alafenamideemtricitabinedolutegravir tenofovir disoproxil fumarateemtricitabinedolutegravir or tenofovir disoSumbul Asif; Evangelia Baxevanidi; Andrew Hill; Willem Venter; Lee Fairlie; Masebole Masenya; Celicia Serenata; Simiso Sokhela; Nomathemba Chandiwana