Browsing by Author "Heather Maher"
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Item Adult and Paediatric Liver TransplantationWits Transplant Data 2020Carolyn Bouter; Russell Britz; Bernd Strobele; Sharan Rambarran; F Van Der Schyff; Lliam Brannigan; Despina Demopoulos; Marisa Beretta; Sarah Berkenfeld; Dinen Parbhoo; Bilal Bobat; Adam Mahomed; M Reynders; Heather Maher; P Gaylard; Harriet Etheredge; Jean Botha; June FabianItem The African Liver Tissue Biorepository Consortium Capacitating PopulationAppropriate Drug Metabolism Pharmacokinetics and Pharmacogenetics Research in Drug Discovery and Development(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS) Collen Masimirembwa; Michele Ramsay; J Botha; E Ellis; Harriet Etheredge; Tracey Hurrell; C Kanji; Heather Maher; Busisiwe Mthembu; Sharan Rambarran; F van der Schyff; Natalie Smyth; Bernd Strobele; E et al; Jerome Loveland; June FabianItem Blood stream infections in children in the first year after liver transplantation at Wits Donald Gordon Medical Centre South AfricaEleanor Duncan; A DeVoll-Zabrocki; Harriet Etheredge; Heather Maher; Carolyn Bouter; P Gaylard; Jerome Loveland; Barry Fabian; Jean BothaItem Coronavirus Host Genomics Study: South Africa (COVIGen-SA)(2022-10-06) Andrew K. May; Heather Seymour; Harriet Etheredge; Heather Maher; Marta C. Nunes; ShabirA.Madhi; SimisoM. Sokhela; W. D. FrancoisVenter; Neil Martinson; Firdaus Nabeemeeah; Cheryl Cohen; Jocelyn Moyes; Sibongile Walaza; Stefano Tempia; Jackie Kleynhans; Anne von Gottberg; Jeremy Nel; Halima Dawood; Ebrahim Variava; Stephen Tollman; Kathleen Kahn; KobusHerbst; EmilyB.Wong; CarolineT.Tiemessen; Alex van Blydenstein; Lyle Murray; Michelle Venter; June Fabian; Miche´le RamsayHowever, continental Africans are yet to be adequately represented in such studies despite the importance of genetic factors in understanding Africa’s response to the pandemic. We describe the development of a research resource for coronavirus host genomics studies in South Africa known as COVIGen-SA—a multicollaborator strategic partnership designed to provide harmonised demographic, clinical, and genetic information specific to Black South Africans with COVID-19. Over 2,000 participants have been recruited to date. Preliminary results on 1,354 SARS-CoV-2 positive participants from four participating studies showed that 64.7% were female, 333 had severe disease, and 329 were people living with HIV. *rough this resource, we aim to provide insights into host genetic factors relevant to African-ancestry populations, using both genome-wide association testing and targeted sequencing of important genomic loci. *is project will promote and enhance partnerships, build skills, and develop resources needed to address the COVID-19 burden and associated risk factors in South African communities.