Browsing by Author "Brent Tipping"

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    Cohort Profile Update Cognition and dementia in the Health and Aging in Africa Longitudinal Study of an INDEPTH community in South Africa HAALSI dementia
    D T Bassil; M T Farrell; Ryan Wagner; A D Brickman; M M Glymour; Brent Tipping; Stephen Tollman; E et al
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    Cohort Profile Update: Cognition and dementia in the Health and Aging in Africa Longitudinal Study of an INDEPTH community in South Africa (HAALSI dementia)
    (2022-08-10) Darina T Bassil; Meagan T Farrell; Ryan G Wagner; Adam M Brickman; M Maria Glymour; Kenneth M Langa; Jennifer J Manly; Joel Salinas; Brent Tipping; Stephen Tollman; Lisa F Berkman
    The Health and Aging in Africa Longitudinal Study of an INDEPTH Community in South Africa (HAALSI) is a harmonized sister study to the US Health and Retirement Study (HRS). Established in 2015, it includes 5059 individuals aged 40 and over, in a rural community in Agincourt, South Africa. • In light of the projected rise of dementia burden in sub-Saharan Africa, the HAALSI Dementia study was launched in 2019 to investigate the prevalence, incidence and risk factors of cognitive decline and dementia in South Africa. • The HAALSI Dementia sample includes 635 individuals, 50 years and older, of whom 99 also participated in an ancillary magnetic resonance imaging (MRI) sub-study. • The HAALSI Dementia study encompasses a comprehensive, culturally sensitive cognitive battery with multidomain psychometric scales, informant interviews and neurological evaluations, and has sufficient overlap with international Harmonized Cognitive Assessment Protocol (HCAP) and HRS studies to enable cross-calibration. • For new collaborative projects and data sharing, please contact Darina Bassil [dbassil@hsph.harvard.edu].
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    Feasibility of an online consensus approach for the diagnosis of cognitive impairment and dementia in rural South Africa
    (2023-03-04) Darina T. Bassil; Meagan T. Farrell; AlbertWeerman; Muqi Guo; Ryan G.Wagner; AdamM. Brickman; M. Maria Glymour; Kenneth M. Langa; Jennifer J. Manly; Brent Tipping; India Butler; Stephen Tollman; Lisa F. Berkman
    INTRODUCTION:We describe the development and feasibility of using an online consensus approach for diagnosing cognitive impairment and dementia in rural South Africa. METHODS: Cognitive assessments, clinical evaluations, and informant interviews from Cognition and Dementia in the Health and Aging in Africa Longitudinal Study (HAALSI Dementia) were reviewed by an expert panel using a web-based platform to assign a diagnosis of cognitively normal, mild cognitive impairment (MCI), or dementia. RESULTS: Six hundred thirty-five participants were assigned a final diagnostic category, with 298 requiring adjudication conference calls. Overall agreement between each rater’s independent diagnosis and final diagnosis (via the portal or consensus conference) was 78.3%. A moderate level of agreement between raters’ individual ratings and the final diagnostic outcomes was observed (average κ coefficient = 0.50).DISCUSSION: Findings show initial feasibility in using an online consensus approach for the diagnosis of cognitive impairment and dementia in remote, rural, and lowresource settings.