Browsing by Author "Anne Von Gottberg"
Now showing 1 - 9 of 9
Results Per Page
Sort Options
Item Detection of Victoria lineage influenza B viruses with K162 and N163 deletions in the hemagglutinin gene South Africa 2018Orienka Hellferscee; Florette Treurnicht; Lucinda Gaelejwe; aLEXANDRA mOERDYK; Gary Reubenson; Meredith McMorrow; Stefano Tempia; Johanna McAnerney; Sibongile Walaza; Nicole Wolter; Anne Von Gottberg; Cheryl CohenItem Difference in mortality among individuals admitted to hospital with COVID19 during the first and second waves in South Africa a cohort studyWaasila jassat; Caroline Mudara; Lovelyn Ozougwu; Stefano Tempia; Lucille Blumberg; E et al; Anne Von Gottberg; Jinal Bhiman; Cheryl Cohen; Sibongile WalazaItem Epidemiology of Pertussis in Individuals of All Ages Hospitalized With Respiratory Illness in South Africa January 2013December 2018Nicole Wolter; Cheryl Cohen; Stefano Tempia; Sibongile Walaza; Fahima Moosa; Mignonette Du Plessis; Meredith L McMorrow; Florette Treurnicht; Orienka Hellferscee; Halima Dawood; Ebrahim Variava; Anne Von GottbergItem Estimated impact of the pneumococcal conjugate vaccine on pneumonia mortality in South Africa 1999 through 2016 An ecological modelling studyJ Kleynhans; Stefano Tempia; Kayoko Shioda; Anne Von Gottberg; Daniel Weinberger; Cheryl CohenItem Nonvaccine serotype pneumococcal carriage in healthy infants in South Africa following introduction of the 13valent pneumococcal conjugate vaccineZ Skosana; Anne Von Gottberg; S Olorunju; Thabo Mohale; Mignonette Du Plessis; T Adams; N MbelleItem SARSCoV2 501YV2 escapes neutralization by South African COVID19 donor plasmaConstantinos Wibmer; Frances Ayres; Tandile Hermanus; Mashudu Madzivhandila; E et al; Bronwen Lambson; Anne Von Gottberg; Cheryl Cohen; Lynn Morris; Jinal Bhiman; Penelope MooreItem The attributable fraction of respiratory syncytial virus among patients of different age with influenza-like illness and severe acute respiratory illness in a high HIV prevalence setting, South Africa, 2012-2016 Running title: The attributable fraction of RSV in South Africa (all ages), South Africa 2012- 2016(2022-11-22) Jocelyn Moyes; Stefano Tempia; Sibongile Walaza; Meredith L. McMorrow; Adam L. Cohen; Florette Treurnicht; Orienka Hellferscee; Nicole Wolter; Anne Von Gottberg; Halima Dawood; Ebrahim Variava; Kathleen Kahn; Shabir A. Madhi; Cheryl CohenIntroduction The detection of respiratory syncytial virus (RSV) in upper airway samples does not necessarily infer causality of illness. Calculating the attributable fraction (AF) of RSV in clinical syndromes could refine disease burden estimates. Methods Using unconditional logistic regression models, we estimated the AF of RSV-associated influenza-like illness (ILI) and severe-acute respiratory illness (SARI) cases by comparing RSVdetection prevalence among ILI and SARI cases to those of healthy controls in South Africa, 2012-2016. The analysis, stratified by HIV serostatus, was conducted in the age categories <1, 1-4, 5-24, 25-44, 45-64, ≥65 years. Results We included 12,048 individuals: 2,687 controls, 5,449 ILI cases and 5,449 SARI cases. RSVAFs for ILI were significant in <1, 1-4, 5-24, 25-44-year age groups: 84.9%(95% confidence interval (CI) 69.3%-92.6%), 74.6%(95%CI 53.6%-86.0%), 60.8%(95%CI 21.4%-80.5%) and 64.1%(95%CI 14.9%-84.9%), respectively. Similarly, significant RSV-AFs for SARI were 95.3%(95%CI 91.1%-97.5) and 83.4%(95%CI 70.9-90.5) in the <1 and 1-4-year age groups respectively. In HIV-infected persons, RSV was significantly associated with ILI cases versus controls in individuals aged 5-44 years. Conclusion High RSV-AFs in young children confirm RSV detection is associated severe respiratory illness in South African children, specifically infants. These estimates will assist with refining burden estimates and cost effectiveness modelsItem The importation and establishment of community transmission of SARSCoV2 during the first eight weeks of the South African COVID19 epidemicKerrigan McCarthy; Stefano Tempia; T Kufa; J Kleynhans; Nicole Wolter; W jassat; J Ebonwu; Anne Von Gottberg; L Erasmus; M Muchengeti; Sibongile Walaza; G Ntshoe; A Shonhiwa; Pinky Manana; Y Pillay; D Moonasar; T Muthivhi; S Mngemane; K Mlisana; K ChettyItem The Role of Molecular Testing in Pediatric Meningitis Surveillance in Southern and East African Countries 20082017Mignonette Du Plessis; Linda de Gouveia; Cesar Freitas; Asamene Abera; Budiaki Lula; A Et Al; Anne Von Gottberg