Study of bismuth complexation with amino acids and biologically active molecules
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Date
2016
Authors
Govender, Dhuneshan
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Abstract
Bismuth(III) has been used in the medicinal industry for many years, but its mechanism of
action is not fully understood and there is very little information on thermodynamic and
kinetic parameters for complex formation. Amino acids are the building blocks of life and
so, by initially simply determining the complexing ability of various amino acids with
bismuth, an indication of how bismuth could interact in the body can slowly be
developed and could assist in the eventual development and design of more effective
bismuth containing drugs.