Impact of Highly Active Anti-Retroviral Therapy on paediatric Human Immuno-Deficiency Virus associated left ventricular dysfunction within the Johannesburg teaching hospital complex
Date
2012-09
Authors
Pepeta, Lungile
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Cardiovascular
disease
is
a
common
complication
of
advanced
HIV
disease
in
both
paediatric
and
adult
patient
groups
and
may
present
with
left
ventricular
(LV)
dysfunction.
Introduction
of
Highly
Active
Antiretroviral
Therapy
(HAART)
has
improved
outcomes
in
patients
presenting
with
LV
dysfunction.
However,
mitochondrial
toxicity,
a
complication
of
HAART,
may
present
with
myocardial
dysfunction.
Description
Research
report
submitted
to
the
Faculty
of
Health
Sciences,
University
of
the
Witwatersrand,
in
partial
fulfilment
of
the
requirements
for
the
degree
MASTER
OF
MEDICINE
(MMED.)
(PAEDIATRICS
AND
CHILD
HEALTH).
Department
of
Paediatrics
and
Child
Health
Johannesburg,
South
Africa,
2012