Kramer, Sydney2018-07-232018-07-231960https://hdl.handle.net/10539/25152A thesis presented to the Faculty of Medicine, University of the Witwatersrand, in fulfilment of the requirements for the degree of Doctor of MedicineSince changes occur in size, shape and haemoglobin content of red cells in disease a classification of the anaemias based on the morphology of the red cell has been widely used ( Wintrobe, 1956 ) . While such classification has a limited usefulness from the diagnostic and therapeutic approach it has two serious defects..enKineticsHematologic DiseasesPorphyria, Acute IntermittentScurvyThesis