Van der Westhuizen, Danielle2021-12-182021-12-182021Van der Westhuizen, Danielle (2021) The synthesis and evaluation of bis-1,2,3-triazolylidene(carbazolide) gold complexes as anti-cancer agents, University of the Witwatersrand, Johannesburg, <http://hdl.handle.net/10539/32435>https://hdl.handle.net/10539/32435A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Faculty of Science, School of Chemistry, University of the Witwatersrand, Johannesburg, 2021Gold pincer complexes were evaluated for their potential as suitable anticancer agents. The use of a multidentate pincer ligand composed of an anionic carbazolide backbone and two flanking 1,2,3 triazol 5 ylidenes trz was proposed for the effective redox stabilization of the gold III complex under physiological conditions.Online resource (182 leaves)enLigands (Biochemistry)Antineoplastic agentsThesis