Charlton, R. W.2018-10-102018-10-101962-09https://hdl.handle.net/10539/25751.A Thesis presented for the degree of Doctor of Medicine at the University of the Witwatersrand SEPTEMBER 1962.Plasmoquine (piasmochin, paiuaquin) was the first synthetic antimalarial drug, and it aroused a great deal of interest when it became available in 1926. Dixon (1933) estimated that at least 415 papers relating to plasmoquine hid appeared in the first 4 years following iti introduction, thereafter the volume of communications decreased somewhat,until fresh interest was stimulated by the Second world <.ar and the horean »,ar with fighting in maiariou. areasenPrimaquineEpidemiologyPharmaceutical PreparationsThesis