Tiemessen., Caroline. T.2019-03-072019-03-071992-08-17https://hdl.handle.net/10539/26525A thesis submitted to the Faculty of Medicine University of the Witwatersrand, Johannesburg for the Degree of Doctor of Philosophy Johannesburg, 1992A distinguishing feature of the human subgroup F adenoviruses, types 40 and 41, is their inability to replicate in cells that permit efficient growth of other adenoviruses. This study was conducted to determine the basis of the viral defect(s) responsible for poor growth in vitroenAdenoviruses, HumanIn Vitro TechniquesDNAThesis