Leboho, Tlabo Caiphus2014-03-052014-03-052014-03-05http://hdl.handle.net10539/14023This thesis describes the application of the Sonogashira coupling reaction to access a variety of 5-and 7-azaindoles derivatives. The background chapter paints a picture about the importance of indole-containing compounds and azaindole-containing compounds. In this first chapter, discovery, synthesis, properties and reactivity of indole and azaindoles were explained.enIndole.Indole alkaloids - Synthesis.Organic compounds.Thesis