Giangregorio, Alfredo2018-06-042018-06-041991-12https://hdl.handle.net/10539/24578A Thesis Submitted to the Faculty of Medicine, in Fulfilment of the Requirements for the Degree of • Doctor of PhilosophyNumerous studies have assessed the effects of single fatty acids on various aspects of lipid metabolism, particularly cancer. Established cell lines have largely been used for this purpose. The choice of control cells, however, has often been inappropriate. There is also a surprising lack of knowledge of the effects of fatty acids in the ‘real world", in which normal cells in vivo are presented with mixtures of dietary fatty acidsenTHE INFLUENCE OF FATTY ACIDS IN VITRO ON MAMMALIAN CELLS FROM SPECIES DIFFERING IN THEIR FATTY ACYL DESATURASE CAPABILITIES.VOL. 1Thesis