Nyiligira., Eric.2018-11-152018-11-152004-09-03https://hdl.handle.net/10539/26044A dissertation submitted to the Faculty of Health Sciences, University of the Witwatersrand, in fulfilment of the requirements for the degree of Master of Pharmacy Johannesburg. 2004As part of investigation of the biological activities of South African plant, a phytochemical and pharmacological investigation was carried out on five indigenous Vitex species; V. obovata ssp. obovata, V.obovata ssp. wilmsii, V. pooara, V. rehmannii and V. zeyheri . The chemical composition of the essential oils was determined using gas chromatography and mass spectrometry, and 1.8-cineole, a- copaene , caryophyllene oxide and y-muurolene were found to be the most abundant constituents in the essential oils of both V. obovatassp. obovataand V. obovata sssp. wilmsii.enPhytochemicalsPharmacologyVitexTuberculosisSilicosisThesis