Phokontsi, Kenyaditswe Charity Petronella2020-02-192020-02-192018Phokontsi, Kenyaditswe Charity Petronella, (2018) An audit of the intraoperative usage of blood products in patients undergoing cardiac surgery on cardiopulmonary bypass, University of the Witwatersrand, Johannesburg, https://hdl.handle.net/10539/28908https://hdl.handle.net/10539/28908A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, in the fulfillment of the requirements for the degree of Masters of Medicine in the branch of Anaesthesiology, Johannesburg, 2018Title: An audit of the intraoperative usage of blood products in patients undergoing cardiac surgery on cardiopulmonary bypass. Background: Transfusion of blood products is increasingly recognised as an independent predictor of poor outcome after cardiac surgery. The study aims to audit blood transfusion usage in a cardiothoracic unit, at a tertiary academic centre. Methods: A descriptive, retrospective, contextual audit. A consecutive convenience sampling method was used. One hundred and twenty-­two adult patients who underwent their first elective cardiac surgery on cardiopulmonary bypass were enrolled. Results: The mean age of the population studied was 46.7 (16.2) years. Patients were predominantly male (60.7%). The mean (SD) body mass index was 21.4 (5.6) kg/m2. Their mean (SD) preoperative haemoglobin and platelet count was 12.8 (2.3) g/dL and 274.4 (121.9) 109/L respectively. Following a clear fluid prime cardiopulmonary bypass technique, with a median (IQR) priming volume of 1500 (1000 -­ 2000) ml, the first mean (SD) haemoglobin on cardiopulmonary bypass was 8.9 (1.6) g/dL. Overall, 110 (90.2%) patients received donor blood products. Eighty-­five (77.3%) patients received red blood cells,103 (93.6%) fresh frozen plasma, and 35 (31.8%) platelet transfusion. A total of 255 red blood cell, 225 fresh frozen plasma and 37 platelet units were transfused. The cell salvage technique was used in 94 (77.0%) patients. The median (IQR) volume of salvaged blood was 535 (250– 754) ml. Conclusion: A high rate of homologous blood product transfusion was found in patients undergoing cardiac surgery in the study.Online resource (93 leaves)enChest--SurgerySurgery, OperativeThesis