Beaton, G. R.2017-11-032017-11-031976http://hdl.handle.net/10539/23364A Thesis Submitted to the Faculty of Science University of the Witwatersrand, Johannesburg for the Degree of Doctor of Philosophy Johannesburg 1976This thesis describes the results of experimental investigation of aspects of the endocrine regulation of growth in the rabbit, rat and man. In particular the role of serum somatomedin and cartilage responsiveness to somatomedin have been examined. Throughout a relationship between the physiological control mechanisms, namely the stimulus and the degree of end- organ responsiveness, and the velocity of growth has been sought.enSerumSomatomedinsCartilageThesis